八個主題模組,以 DHA 的內容領域為基礎,這是目前唯一公開的阿聯酋藥師大綱。DOH 並未公布自己的大綱,而且阿聯酋各主管機關共用執照規定。本頁不宣稱存在 DOH 藍圖。
依阿聯酋藥師考試題型撰寫的單一最佳答案題,並提供限時模擬考。
每道題都附有解析與公開參考資料。
免費範例題
以下是免費範例題組中的原創練習題,每題都附有答案、解析與公開參考資料。
1. A 66-year-old man with chronic stable angina is prescribed immediate-release isosorbide mononitrate 20 mg twice daily. He asks when to take his doses. Which dosing schedule best prevents nitrate tolerance?
08:00, 16:00 and 24:00
10:00 and 22:00
08:00 and 15:00
08:00 and 20:00
正確答案
C. 08:00 and 15:00
The labeling for immediate-release isosorbide mononitrate recommends giving the two daily doses 7 hours apart, for example on waking and 7 hours later. This leaves a long nitrate-free interval overnight that limits tolerance. Doses 12 hours apart, or three times daily, keep nitrate levels sustained around the clock and promote tolerance.
2. A 54-year-old man with type 2 diabetes takes metformin 1 g twice daily and dapagliflozin 10 mg daily. He is admitted after 2 days of vomiting and very poor oral intake. Results: plasma glucose 10.8 mmol/L, arterial pH 7.18, bicarbonate 11 mmol/L, serum beta-hydroxybutyrate 5.2 mmol/L, lactate 1.4 mmol/L, serum osmolality 296 mOsm/kg. Which diagnosis best explains these findings?
Euglycaemic diabetic ketoacidosis
Hyperosmolar hyperglycaemic state
Metformin-associated lactic acidosis
Simple starvation ketosis
正確答案
A. Euglycaemic diabetic ketoacidosis
SGLT2 inhibitors such as dapagliflozin can cause ketoacidosis with only modestly raised glucose, especially during reduced oral intake, vomiting, surgery or acute illness. Here a high beta-hydroxybutyrate with severe acidosis and glucose below 14 mmol/L fits euglycaemic DKA. The normal lactate excludes metformin-associated lactic acidosis, and the normal osmolality excludes a hyperosmolar state. Simple starvation ketosis does not cause this degree of acidaemia.
3. A 34-year-old man in the emergency department requires an intravenous phenytoin sodium loading dose by intermittent infusion. Which diluent is most appropriate to minimise the risk of precipitation?
Lactated Ringer's injection
Dextrose 5% in 0.45% sodium chloride
5% dextrose injection
0.9% sodium chloride injection
正確答案
D. 0.9% sodium chloride injection
Phenytoin sodium injection is formulated at a high pH with propylene glycol and ethanol; the labelling specifies dilution in normal saline only for infusion, with an in-line filter, and administration soon after preparation. Dextrose-containing solutions lower the pH and cause phenytoin to precipitate. Other solutions are not recommended in the labelling because compatibility is not assured.
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