藥物交互作用
Abobotulinumtoxina + Oxybutynin
嚴重程度: 中度
Abobotulinumtoxina and Oxybutynin: moderate interaction.
最後更新
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摘要
Anticholinergic drugs such as oxybutynin may add to the effects of botulinum toxin, increasing the risk of excessive muscle weakness and systemic anticholinergic effects such as dry mouth, constipation and urinary retention.
用白話說明這項交互作用的意義
Abobotulinumtoxina and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive anticholinergic and neuromuscular-blocking effects at cholinergic transmission.
處置方式
Monitor for generalized weakness, swallowing or breathing difficulty and anticholinergic effects after injection; reduce oxybutynin if these appear.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Oxybutynin 的其他交互作用
常見問題
Can I take Abobotulinumtoxina with Oxybutynin?
MediHelp rates the interaction as moderate. Abobotulinumtoxina and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anticholinergic drugs such as oxybutynin may add to the effects of botulinum toxin, increasing the risk of excessive muscle weakness and systemic anticholinergic effects such as dry mouth, constipation and urinary retention.
How serious is the interaction between Abobotulinumtoxina and Oxybutynin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for generalized weakness, swallowing or breathing difficulty and anticholinergic effects after injection; reduce oxybutynin if these appear.
What other medicines interact with Oxybutynin?
MediHelp also lists interactions of Oxybutynin with, for example, Bethanechol, Clozapine, Potassium chloride. The full list is on the Oxybutynin page.
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