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藥物交互作用

Acetylcysteine + Activated charcoal

嚴重程度: 輕微

Acetylcysteine and Activated charcoal: minor interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Activated charcoal may adsorb some oral acetylcysteine and reduce its absorption, but studies show this has little effect on its efficacy in acetaminophen overdose. Charcoal use should not delay or preclude acetylcysteine therapy.

用白話說明這項交互作用的意義

Acetylcysteine and Activated charcoal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Acetylcysteine belongs to Respiratory; Activated charcoal belongs to Gastrointestinal Tract.

證據等級: Moderate

為什麼會發生

Adsorption of oral acetylcysteine to activated charcoal in the gut lumen may reduce its absorption.

處置方式

Give charcoal when indicated and do not withhold acetylcysteine; use intravenous acetylcysteine or monitor response if oral dosing is used, with doses guided by acetaminophen levels.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Acetylcysteine with Activated charcoal?

MediHelp rates the interaction as minor. Acetylcysteine and Activated charcoal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Activated charcoal may adsorb some oral acetylcysteine and reduce its absorption, but studies show this has little effect on its efficacy in acetaminophen overdose. Charcoal use should not delay or preclude acetylcysteine therapy.

How serious is the interaction between Acetylcysteine and Activated charcoal?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give charcoal when indicated and do not withhold acetylcysteine; use intravenous acetylcysteine or monitor response if oral dosing is used, with doses guided by acetaminophen levels.

What other medicines interact with Acetylcysteine?

MediHelp also lists interactions of Acetylcysteine with, for example, Nitroglycerin, Nitroglycerin po, Nitroglycerin rectal. The full list is on the Acetylcysteine page.

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