藥物交互作用
Aclidinium + Trospium
嚴重程度: 中度
Aclidinium and Trospium: moderate interaction.
最後更新
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摘要
Both are antimuscarinics, and inhaled aclidinium has low systemic absorption. Combined use may still add to dry mouth, constipation and urinary retention, and the combination may worsen glaucoma or bladder outlet obstruction.
用白話說明這項交互作用的意義
Aclidinium and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive antimuscarinic effects.
處置方式
Monitor for urinary retention, constipation and worsening of narrow-angle glaucoma. Avoid the combination in patients with these conditions.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Trospium 的其他交互作用
常見問題
Can I take Aclidinium with Trospium?
MediHelp rates the interaction as moderate. Aclidinium and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinics, and inhaled aclidinium has low systemic absorption. Combined use may still add to dry mouth, constipation and urinary retention, and the combination may worsen glaucoma or bladder outlet obstruction.
How serious is the interaction between Aclidinium and Trospium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation and worsening of narrow-angle glaucoma. Avoid the combination in patients with these conditions.
What other medicines interact with Trospium?
MediHelp also lists interactions of Trospium with, for example, Clozapine, Pramlintide, Thioridazine. The full list is on the Trospium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
