藥物交互作用
Adefovir + Emtricitabine
嚴重程度: 中度
Adefovir and Emtricitabine: moderate interaction.
最後更新
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摘要
Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.
用白話說明這項交互作用的意義
Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Adefovir belongs to Anti Virals; Emtricitabine belongs to Anti Virals.
為什麼會發生
Competition for renal tubular secretion and additive effects on renal function.
處置方式
Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Adefovir 的其他交互作用
Emtricitabine 的其他交互作用
常見問題
Can I take Adefovir with Emtricitabine?
MediHelp rates the interaction as moderate. Adefovir and Emtricitabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are eliminated by the kidneys through filtration and active tubular secretion. Competition for secretion may raise concentrations of either drug, and adefovir's nephrotoxicity may further impair emtricitabine clearance.
How serious is the interaction between Adefovir and Emtricitabine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function regularly and adjust the dosing interval of emtricitabine if creatinine clearance falls.
What other medicines interact with Adefovir?
MediHelp also lists interactions of Adefovir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Amikacin, Amphotericin b. The full list is on the Adefovir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
