藥物交互作用
Adenovirus types 4 and 7 live + Cisplatin
嚴重程度: 嚴重
Adenovirus types 4 and 7 live and Cisplatin: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Cisplatin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine could cause uncontrolled vaccine-virus replication and disease. The vaccine response may also be inadequate.
用白話說明這項交互作用的意義
Adenovirus types 4 and 7 live and Cisplatin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Chemotherapy-induced immunosuppression impairs control of live attenuated vaccine virus and reduces immune response.
處置方式
Avoid the live vaccine during cisplatin therapy and for at least 3 months after stopping. Use only when immune recovery is confirmed.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cisplatin 的其他交互作用
常見問題
Can I take Adenovirus types 4 and 7 live with Cisplatin?
MediHelp rates the interaction as major. Adenovirus types 4 and 7 live and Cisplatin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cisplatin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine could cause uncontrolled vaccine-virus replication and disease. The vaccine response may also be inadequate.
How serious is the interaction between Adenovirus types 4 and 7 live and Cisplatin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live vaccine during cisplatin therapy and for at least 3 months after stopping. Use only when immune recovery is confirmed.
What other medicines interact with Cisplatin?
MediHelp also lists interactions of Cisplatin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Cisplatin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
