藥物交互作用
Alendronate + Sucroferric oxyhydroxide
嚴重程度: 中度
Alendronate and Sucroferric oxyhydroxide: moderate interaction.
最後更新
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摘要
Sucroferric oxyhydroxide is a phosphate binder containing iron that can bind alendronate in the gut. This lowers alendronate absorption and may reduce its efficacy.
用白話說明這項交互作用的意義
Alendronate and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alendronate belongs to Musculoskeletal; Sucroferric oxyhydroxide belongs to Genitourinary.
為什麼會發生
Binding or chelation of alendronate by iron-containing phosphate binder in the GI tract reduces absorption.
處置方式
Take alendronate with plain water at least 1 hour before sucroferric oxyhydroxide, and never at the same time.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Alendronate 的其他交互作用
Sucroferric oxyhydroxide 的其他交互作用
常見問題
Can I take Alendronate with Sucroferric oxyhydroxide?
MediHelp rates the interaction as moderate. Alendronate and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sucroferric oxyhydroxide is a phosphate binder containing iron that can bind alendronate in the gut. This lowers alendronate absorption and may reduce its efficacy.
How serious is the interaction between Alendronate and Sucroferric oxyhydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take alendronate with plain water at least 1 hour before sucroferric oxyhydroxide, and never at the same time.
What other medicines interact with Alendronate?
MediHelp also lists interactions of Alendronate with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Alendronate page.
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