藥物交互作用
Levothyroxine + Sucroferric oxyhydroxide
嚴重程度: 中度
Levothyroxine and Sucroferric oxyhydroxide: moderate interaction.
最後更新
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摘要
Iron-based phosphate binders can bind oral levothyroxine in the gut and reduce its absorption, potentially raising TSH. Parenteral levothyroxine is not affected.
用白話說明這項交互作用的意義
Levothyroxine and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levothyroxine belongs to Endocrine; Sucroferric oxyhydroxide belongs to Genitourinary.
為什麼會發生
Iron binds or chelates levothyroxine in the gastrointestinal tract, reducing absorption.
處置方式
Give oral levothyroxine at least 4 hours before sucroferric oxyhydroxide. Monitor TSH after starting or changing the binder.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Levothyroxine 的其他交互作用
Sucroferric oxyhydroxide 的其他交互作用
常見問題
Can I take Levothyroxine with Sucroferric oxyhydroxide?
MediHelp rates the interaction as moderate. Levothyroxine and Sucroferric oxyhydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron-based phosphate binders can bind oral levothyroxine in the gut and reduce its absorption, potentially raising TSH. Parenteral levothyroxine is not affected.
How serious is the interaction between Levothyroxine and Sucroferric oxyhydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral levothyroxine at least 4 hours before sucroferric oxyhydroxide. Monitor TSH after starting or changing the binder.
What other medicines interact with Levothyroxine?
MediHelp also lists interactions of Levothyroxine with, for example, Cholestyramine, Sodium iodide i-131, Tiratricol. The full list is on the Levothyroxine page.
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