藥物交互作用
Alfentanil + Brexpiprazole
嚴重程度: 嚴重
Alfentanil and Brexpiprazole: major interaction.
最後更新
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摘要
Opioids combined with other CNS depressants can cause profound sedation, respiratory depression, hypotension, coma and death. Brexpiprazole adds sedative and orthostatic effects to alfentanil.
用白話說明這項交互作用的意義
Alfentanil and Brexpiprazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression.
處置方式
Use together only when alternative options are inadequate, with the lowest effective doses and shortest duration. Monitor for sedation, respiratory depression and hypotension.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Brexpiprazole 的其他交互作用
常見問題
Can I take Alfentanil with Brexpiprazole?
MediHelp rates the interaction as major. Alfentanil and Brexpiprazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids combined with other CNS depressants can cause profound sedation, respiratory depression, hypotension, coma and death. Brexpiprazole adds sedative and orthostatic effects to alfentanil.
How serious is the interaction between Alfentanil and Brexpiprazole?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use together only when alternative options are inadequate, with the lowest effective doses and shortest duration. Monitor for sedation, respiratory depression and hypotension.
What other medicines interact with Brexpiprazole?
MediHelp also lists interactions of Brexpiprazole with, for example, Amisulpride, Apalutamide, Atazanavir. The full list is on the Brexpiprazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
