藥物交互作用
Allogeneic cultured keratinocytes and fibroblasts + Silver sulfadiazine
嚴重程度: 中度
Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine: moderate interaction.
最後更新
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摘要
Silver sulfadiazine applied to a wound leaves silver ions that are toxic to living cells. This can reduce the viability of the cultured keratinocytes and fibroblasts in the cell-based skin product and impair graft take.
用白話說明這項交互作用的意義
Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Local cytotoxicity of silver ions toward cultured human keratinocytes and fibroblasts.
處置方式
Do not apply silver sulfadiazine or silver dressings to the site before or at the time of application of the cellular product. Rinse the wound bed thoroughly if silver was previously used.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Silver sulfadiazine 的其他交互作用
常見問題
Can I take Allogeneic cultured keratinocytes and fibroblasts with Silver sulfadiazine?
MediHelp rates the interaction as moderate. Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Silver sulfadiazine applied to a wound leaves silver ions that are toxic to living cells. This can reduce the viability of the cultured keratinocytes and fibroblasts in the cell-based skin product and impair graft take.
How serious is the interaction between Allogeneic cultured keratinocytes and fibroblasts and Silver sulfadiazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not apply silver sulfadiazine or silver dressings to the site before or at the time of application of the cellular product. Rinse the wound bed thoroughly if silver was previously used.
What other medicines interact with Silver sulfadiazine?
MediHelp also lists interactions of Silver sulfadiazine with, for example, Collagenase, Papain, Trypsin. The full list is on the Silver sulfadiazine page.
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