藥物交互作用
Alprazolam + Ganaxolone
嚴重程度: 中度
Alprazolam and Ganaxolone: moderate interaction.
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摘要
Ganaxolone is a neuroactive steroid with sedating effects, and combined use with alprazolam can add to somnolence, dizziness and respiratory depression.
用白話說明這項交互作用的意義
Alprazolam and Ganaxolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alprazolam belongs to Central Nervous System; Ganaxolone belongs to Central Nervous System.
為什麼會發生
Additive CNS depression via positive modulation of GABA-A receptors.
處置方式
Monitor for excessive sedation and reduce the dose of either drug if somnolence is troublesome. Counsel patients on driving and machinery.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Alprazolam 的其他交互作用
Ganaxolone 的其他交互作用
常見問題
Can I take Alprazolam with Ganaxolone?
MediHelp rates the interaction as moderate. Alprazolam and Ganaxolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ganaxolone is a neuroactive steroid with sedating effects, and combined use with alprazolam can add to somnolence, dizziness and respiratory depression.
How serious is the interaction between Alprazolam and Ganaxolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and reduce the dose of either drug if somnolence is troublesome. Counsel patients on driving and machinery.
What other medicines interact with Alprazolam?
MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
