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藥物交互作用

Aluminum hydroxide + Sarecycline

嚴重程度: 中度

Aluminum hydroxide and Sarecycline: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Aluminum can bind sarecycline and reduce absorption. Reduced exposure may weaken acne treatment effect.

用白話說明這項交互作用的意義

Aluminum hydroxide and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Aluminum hydroxide belongs to Gastrointestinal Tract; Sarecycline belongs to Anti Bacterial.

證據等級: Moderate

為什麼會發生

Polyvalent aluminum cations chelate the tetracycline-class drug in the gut, decreasing absorption.

處置方式

Separate sarecycline from aluminum antacids by at least 2 to 3 hours, giving sarecycline first.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Aluminum hydroxide with Sarecycline?

MediHelp rates the interaction as moderate. Aluminum hydroxide and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum can bind sarecycline and reduce absorption. Reduced exposure may weaken acne treatment effect.

How serious is the interaction between Aluminum hydroxide and Sarecycline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sarecycline from aluminum antacids by at least 2 to 3 hours, giving sarecycline first.

What other medicines interact with Aluminum hydroxide?

MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.

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