藥物交互作用
Amoxapine + Palonosetron
嚴重程度: 中度
Amoxapine and Palonosetron: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Amoxapine is an antidepressant with serotonergic activity, and 5-HT3 antagonists have been linked to rare serotonin syndrome cases with such drugs. The risk with palonosetron is low and mostly theoretical.
用白話說明這項交互作用的意義
Amoxapine and Palonosetron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Possible additive serotonergic effect; not well established.
處置方式
Monitor for signs of serotonin syndrome such as agitation, tremor, clonus and fever. Stop the agents and give supportive care if it occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Palonosetron 的其他交互作用
常見問題
Can I take Amoxapine with Palonosetron?
MediHelp rates the interaction as moderate. Amoxapine and Palonosetron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amoxapine is an antidepressant with serotonergic activity, and 5-HT3 antagonists have been linked to rare serotonin syndrome cases with such drugs. The risk with palonosetron is low and mostly theoretical.
How serious is the interaction between Amoxapine and Palonosetron?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of serotonin syndrome such as agitation, tremor, clonus and fever. Stop the agents and give supportive care if it occurs.
What other medicines interact with Palonosetron?
MediHelp also lists interactions of Palonosetron with, for example, Apomorphine, Isocarboxazid, Phenelzine. The full list is on the Palonosetron page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
