藥物交互作用
Amoxapine + Pimozide
嚴重程度: 禁忌併用
Amoxapine and Pimozide: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Both agents can prolong the QT interval, and pimozide carries a notable torsades de pointes risk. Combined use increases the chance of serious ventricular arrhythmia.
用白話說明這項交互作用的意義
Amoxapine and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Additive QT prolongation via cardiac potassium channel blockade.
處置方式
Do not co-administer. Choose an antidepressant with less QT liability.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pimozide 的其他交互作用
常見問題
Can I take Amoxapine with Pimozide?
MediHelp rates the interaction as contraindicated. Amoxapine and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents can prolong the QT interval, and pimozide carries a notable torsades de pointes risk. Combined use increases the chance of serious ventricular arrhythmia.
How serious is the interaction between Amoxapine and Pimozide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer. Choose an antidepressant with less QT liability.
What other medicines interact with Pimozide?
MediHelp also lists interactions of Pimozide with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pimozide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
