藥物交互作用
Ampicillin + Demeclocycline
嚴重程度: 中度
Ampicillin and Demeclocycline: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older clinical reports, but it may matter in serious infections such as meningitis.
用白話說明這項交互作用的意義
Ampicillin and Demeclocycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Tetracycline-induced inhibition of bacterial growth reduces the activity of cell-wall-active beta-lactams.
處置方式
Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ampicillin 的其他交互作用
常見問題
Can I take Ampicillin with Demeclocycline?
MediHelp rates the interaction as moderate. Ampicillin and Demeclocycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines can reduce the killing effect of penicillins on bacteria that need active growth. Evidence is mostly in vitro and from older clinical reports, but it may matter in serious infections such as meningitis.
How serious is the interaction between Ampicillin and Demeclocycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining in serious infections that need bactericidal therapy. If unavoidable, monitor clinical response closely.
What other medicines interact with Ampicillin?
MediHelp also lists interactions of Ampicillin with, for example, Allopurinol, Bcg vaccine live, Chloramphenicol. The full list is on the Ampicillin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
