藥物交互作用
Antithrombin alfa + Vitamin e
嚴重程度: 輕微
Antithrombin alfa and Vitamin e: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Antithrombin alfa is a recombinant anticoagulant, and very high doses of vitamin E may modestly impair clotting. Combined use could theoretically raise bleeding risk, but at ordinary vitamin E intakes the effect is unlikely to be meaningful.
用白話說明這項交互作用的意義
Antithrombin alfa and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
為什麼會發生
Theoretical additive anticoagulant effect, as high-dose vitamin E antagonizes vitamin K-dependent clotting and inhibits platelets.
處置方式
Avoid megadose vitamin E while the patient is receiving antithrombin therapy. Monitor for bleeding and coagulation parameters as per routine care.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Vitamin e 的其他交互作用
常見問題
Can I take Antithrombin alfa with Vitamin e?
MediHelp rates the interaction as minor. Antithrombin alfa and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antithrombin alfa is a recombinant anticoagulant, and very high doses of vitamin E may modestly impair clotting. Combined use could theoretically raise bleeding risk, but at ordinary vitamin E intakes the effect is unlikely to be meaningful.
How serious is the interaction between Antithrombin alfa and Vitamin e?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid megadose vitamin E while the patient is receiving antithrombin therapy. Monitor for bleeding and coagulation parameters as per routine care.
What other medicines interact with Vitamin e?
MediHelp also lists interactions of Vitamin e with, for example, Betrixaban, Phenindione, Selumetinib. The full list is on the Vitamin e page.
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