藥物交互作用
Asenapine + Carbinoxamine
嚴重程度: 中度
Asenapine and Carbinoxamine: moderate interaction.
最後更新
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摘要
Carbinoxamine is a sedating first-generation antihistamine with anticholinergic effects, and asenapine is also sedating. Together they increase drowsiness, impair performance and may add anticholinergic effects.
用白話說明這項交互作用的意義
Asenapine and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Asenapine belongs to Central Nervous System; Carbinoxamine belongs to Respiratory.
為什麼會發生
Additive CNS depression via histamine H1 blockade and antipsychotic receptor antagonism.
處置方式
Advise against driving or hazardous tasks and monitor for oversedation. Consider a non-sedating antihistamine.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Asenapine 的其他交互作用
Carbinoxamine 的其他交互作用
常見問題
Can I take Asenapine with Carbinoxamine?
MediHelp rates the interaction as moderate. Asenapine and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbinoxamine is a sedating first-generation antihistamine with anticholinergic effects, and asenapine is also sedating. Together they increase drowsiness, impair performance and may add anticholinergic effects.
How serious is the interaction between Asenapine and Carbinoxamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise against driving or hazardous tasks and monitor for oversedation. Consider a non-sedating antihistamine.
What other medicines interact with Asenapine?
MediHelp also lists interactions of Asenapine with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Asenapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
