藥物交互作用
Amobarbital + Carbinoxamine
嚴重程度: 中度
Amobarbital and Carbinoxamine: moderate interaction.
最後更新
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摘要
Carbinoxamine is a sedating antihistamine, and with a barbiturate it produces additive drowsiness and impaired alertness. Elderly patients and children are at particular risk of excess sedation.
用白話說明這項交互作用的意義
Amobarbital and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amobarbital belongs to Central Nervous System; Carbinoxamine belongs to Respiratory.
為什麼會發生
Additive CNS depression from histamine H1 blockade and barbiturate GABA-A potentiation.
處置方式
Reduce doses if drowsiness occurs and advise against driving or alcohol. Consider a non-sedating antihistamine when appropriate.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amobarbital 的其他交互作用
Carbinoxamine 的其他交互作用
常見問題
Can I take Amobarbital with Carbinoxamine?
MediHelp rates the interaction as moderate. Amobarbital and Carbinoxamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbinoxamine is a sedating antihistamine, and with a barbiturate it produces additive drowsiness and impaired alertness. Elderly patients and children are at particular risk of excess sedation.
How serious is the interaction between Amobarbital and Carbinoxamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reduce doses if drowsiness occurs and advise against driving or alcohol. Consider a non-sedating antihistamine when appropriate.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
