藥物交互作用
Azelaic acid + Urea
嚴重程度: 輕微
Azelaic acid and Urea: minor interaction.
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
用白話說明這項交互作用的意義
Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelaic acid belongs to Dermatology; Urea belongs to Miscellaneous.
為什麼會發生
Additive local irritation, with urea's keratolytic and hydrating action possibly increasing penetration of azelaic acid.
處置方式
If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
參考資料
Azelaic acid 的其他交互作用
Urea 的其他交互作用
常見問題
Can I take Azelaic acid with Urea?
MediHelp rates the interaction as minor. Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
How serious is the interaction between Azelaic acid and Urea?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
What other medicines interact with Azelaic acid?
MediHelp also lists interactions of Azelaic acid with, for example, Tretinoin. The full list is on the Azelaic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。