藥物交互作用
Azelaic acid + Tretinoin
嚴重程度: 輕微
Azelaic acid and Tretinoin: minor interaction.
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Using both topical agents together can cause additive local irritation such as redness, dryness, burning and peeling. The combination is used deliberately in some acne and hyperpigmentation regimens, and irritation is usually manageable. Patients with sensitive skin or rosacea are most affected.
用白話說明這項交互作用的意義
Azelaic acid and Tretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelaic acid belongs to Dermatology; Tretinoin belongs to Dermatology.
為什麼會發生
Pharmacodynamic additive local irritation from tretinoin-induced epidermal turnover and the mild irritant effect of azelaic acid.
處置方式
Apply at different times, for example azelaic acid in the morning and tretinoin at night, or alternate days at the start. Begin with low frequency or strength and use a moisturizer.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
參考資料
- Finacea (azelaic acid) Gel Prescribing Information — FDA Label
- Retin-A (tretinoin) Prescribing Information — FDA Label
Azelaic acid 的其他交互作用
Tretinoin 的其他交互作用
常見問題
Can I take Azelaic acid with Tretinoin?
MediHelp rates the interaction as minor. Azelaic acid and Tretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Using both topical agents together can cause additive local irritation such as redness, dryness, burning and peeling. The combination is used deliberately in some acne and hyperpigmentation regimens, and irritation is usually manageable. Patients with sensitive skin or rosacea are most affected.
How serious is the interaction between Azelaic acid and Tretinoin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Apply at different times, for example azelaic acid in the morning and tretinoin at night, or alternate days at the start. Begin with low frequency or strength and use a moisturizer.
What other medicines interact with Azelaic acid?
MediHelp also lists interactions of Azelaic acid with, for example, Urea. The full list is on the Azelaic acid page.
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