藥物交互作用
Bacitracin + Colistin
嚴重程度: 嚴重
Bacitracin and Colistin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Systemic bacitracin is markedly nephrotoxic, and combining it with colistin compounds the risk of kidney injury. Neurotoxicity and neuromuscular effects may also be additive.
用白話說明這項交互作用的意義
Bacitracin and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Colistin belongs to Anti Bacterial.
為什麼會發生
Additive nephrotoxicity through renal tubular injury.
處置方式
Avoid systemic combination; if unavoidable, monitor renal function daily and adjust doses to creatinine clearance.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Colistin 的其他交互作用
Bacitracin 的其他交互作用
常見問題
Can I take Bacitracin with Colistin?
MediHelp rates the interaction as major. Bacitracin and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic bacitracin is markedly nephrotoxic, and combining it with colistin compounds the risk of kidney injury. Neurotoxicity and neuromuscular effects may also be additive.
How serious is the interaction between Bacitracin and Colistin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic combination; if unavoidable, monitor renal function daily and adjust doses to creatinine clearance.
What other medicines interact with Colistin?
MediHelp also lists interactions of Colistin with, for example, Polymyxin b, Amikacin, Amphotericin b deoxycholate. The full list is on the Colistin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
