藥物交互作用
Bacitracin + Ganciclovir
嚴重程度: 嚴重
Bacitracin and Ganciclovir: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Ganciclovir is cleared by the kidney and needs dose adjustment when renal function falls. Systemic bacitracin is nephrotoxic, and its use can reduce ganciclovir clearance and raise exposure to ganciclovir's marrow toxicity, while adding to renal injury.
用白話說明這項交互作用的意義
Bacitracin and Ganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Ganciclovir belongs to Anti Virals.
為什麼會發生
Additive nephrotoxicity, with reduced renal elimination of ganciclovir when kidney function declines.
處置方式
Avoid systemic bacitracin where alternatives exist. If both are needed, monitor serum creatinine and blood counts closely and adjust the ganciclovir dose to creatinine clearance.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ganciclovir 的其他交互作用
Bacitracin 的其他交互作用
常見問題
Can I take Bacitracin with Ganciclovir?
MediHelp rates the interaction as major. Bacitracin and Ganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ganciclovir is cleared by the kidney and needs dose adjustment when renal function falls. Systemic bacitracin is nephrotoxic, and its use can reduce ganciclovir clearance and raise exposure to ganciclovir's marrow toxicity, while adding to renal injury.
How serious is the interaction between Bacitracin and Ganciclovir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic bacitracin where alternatives exist. If both are needed, monitor serum creatinine and blood counts closely and adjust the ganciclovir dose to creatinine clearance.
What other medicines interact with Ganciclovir?
MediHelp also lists interactions of Ganciclovir with, for example, Cilastatin-imipenem, Didanosine, Imipenem / cilastatin. The full list is on the Ganciclovir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
