藥物交互作用
Basiliximab + Efgartigimod alfa
嚴重程度: 中度
Basiliximab and Efgartigimod alfa: moderate interaction.
最後更新
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摘要
Efgartigimod blocks the neonatal Fc receptor and speeds clearance of IgG, so IgG-based antibodies such as basiliximab may reach lower exposure. This could reduce the degree of IL-2 receptor blockade during induction.
用白話說明這項交互作用的意義
Basiliximab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Efgartigimod alfa belongs to Miscellaneous.
為什麼會發生
Blockade of FcRn reduces IgG recycling and increases clearance of IgG monoclonal antibodies.
處置方式
Avoid timing efgartigimod cycles around basiliximab doses when possible and monitor for loss of immunosuppressive effect or graft rejection.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Basiliximab 的其他交互作用
- Basiliximab + Bcg vaccine live 禁忌併用
- Basiliximab + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Basiliximab + Measles mumps and rubella vaccine 禁忌併用
- Basiliximab + Measles mumps and rubella vaccine live 禁忌併用
- Basiliximab + Measles mumps rubella and varicella vaccine live 禁忌併用
- Basiliximab + Measles vaccine 禁忌併用
Efgartigimod alfa 的其他交互作用
常見問題
Can I take Basiliximab with Efgartigimod alfa?
MediHelp rates the interaction as moderate. Basiliximab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Efgartigimod blocks the neonatal Fc receptor and speeds clearance of IgG, so IgG-based antibodies such as basiliximab may reach lower exposure. This could reduce the degree of IL-2 receptor blockade during induction.
How serious is the interaction between Basiliximab and Efgartigimod alfa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid timing efgartigimod cycles around basiliximab doses when possible and monitor for loss of immunosuppressive effect or graft rejection.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
