藥物交互作用
Bevacizumab + Efgartigimod alfa
嚴重程度: 中度
Bevacizumab and Efgartigimod alfa: moderate interaction.
最後更新
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摘要
Efgartigimod blocks the neonatal Fc receptor, which normally recycles IgG, so it may speed clearance of IgG-based drugs. Bevacizumab is an IgG1 antibody and its exposure could fall.
用白話說明這項交互作用的意義
Bevacizumab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bevacizumab belongs to Oncology; Efgartigimod alfa belongs to Miscellaneous.
為什麼會發生
FcRn blockade reduces IgG recycling and shortens the half-life of IgG monoclonal antibodies.
處置方式
Monitor for reduced bevacizumab response; if prolonged therapy is essential, consider timing or alternatives.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Bevacizumab 的其他交互作用
Efgartigimod alfa 的其他交互作用
常見問題
Can I take Bevacizumab with Efgartigimod alfa?
MediHelp rates the interaction as moderate. Bevacizumab and Efgartigimod alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Efgartigimod blocks the neonatal Fc receptor, which normally recycles IgG, so it may speed clearance of IgG-based drugs. Bevacizumab is an IgG1 antibody and its exposure could fall.
How serious is the interaction between Bevacizumab and Efgartigimod alfa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced bevacizumab response; if prolonged therapy is essential, consider timing or alternatives.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Dengue vaccine. The full list is on the Bevacizumab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
