藥物交互作用
Bcg vaccine live + Hydroxyurea
嚴重程度: 嚴重
Bcg vaccine live and Hydroxyurea: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Hydroxyurea is myelosuppressive and immunosuppressive. A live BCG vaccine may be less effective and may cause disseminated BCG infection.
用白話說明這項交互作用的意義
Bcg vaccine live and Hydroxyurea can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Immunosuppression impairs the vaccine response and permits replication of live bacteria.
處置方式
Avoid live vaccines during hydroxyurea therapy. Defer vaccination until immune recovery.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Hydroxyurea 的其他交互作用
常見問題
Can I take Bcg vaccine live with Hydroxyurea?
MediHelp rates the interaction as major. Bcg vaccine live and Hydroxyurea can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Hydroxyurea is myelosuppressive and immunosuppressive. A live BCG vaccine may be less effective and may cause disseminated BCG infection.
How serious is the interaction between Bcg vaccine live and Hydroxyurea?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during hydroxyurea therapy. Defer vaccination until immune recovery.
What other medicines interact with Hydroxyurea?
MediHelp also lists interactions of Hydroxyurea with, for example, Didanosine, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel. The full list is on the Hydroxyurea page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
