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藥物交互作用

Bcg vaccine live + Penicillin g

嚴重程度: 中度

Bcg vaccine live and Penicillin g: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host, which could lessen the immune response. Penicillins have limited documented activity against BCG, so the effect is mainly theoretical.

用白話說明這項交互作用的意義

Bcg vaccine live and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Low

為什麼會發生

Antibacterial activity could reduce replication of the live attenuated organism, though penicillin activity against Mycobacterium bovis BCG is limited.

處置方式

Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of a penicillin.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
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常見問題

Can I take Bcg vaccine live with Penicillin g?

MediHelp rates the interaction as moderate. Bcg vaccine live and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host, which could lessen the immune response. Penicillins have limited documented activity against BCG, so the effect is mainly theoretical.

How serious is the interaction between Bcg vaccine live and Penicillin g?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of a penicillin.

What other medicines interact with Penicillin g?

MediHelp also lists interactions of Penicillin g with, for example, Amifampridine, Amiloride, Cholera vaccine. The full list is on the Penicillin g page.

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