藥物交互作用
Deflazacort + Penicillin g
嚴重程度: 中度
Deflazacort and Penicillin g: moderate interaction.
最後更新
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摘要
High-dose penicillin G can cause hypokalemia through delivery of a nonreabsorbable anion to the distal nephron, which increases potassium loss. Deflazacort, a corticosteroid, has mineralocorticoid activity that can also lower potassium, so the effects may add together.
用白話說明這項交互作用的意義
Deflazacort and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Penicillin g belongs to Anti Bacterial.
為什麼會發生
Additive renal potassium wasting from penicillin G and corticosteroid mineralocorticoid effect.
處置方式
Monitor serum potassium during high-dose penicillin G therapy with deflazacort and replace potassium as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Penicillin g 的其他交互作用
Deflazacort 的其他交互作用
- Adenovirus types 4 and 7 live + Deflazacort 禁忌併用
- Bcg vaccine live + Deflazacort 禁忌併用
- Deflazacort + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Deflazacort + Measles mumps and rubella vaccine 禁忌併用
- Deflazacort + Measles mumps and rubella vaccine live 禁忌併用
- Deflazacort + Measles mumps rubella and varicella vaccine live 禁忌併用
常見問題
Can I take Deflazacort with Penicillin g?
MediHelp rates the interaction as moderate. Deflazacort and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High-dose penicillin G can cause hypokalemia through delivery of a nonreabsorbable anion to the distal nephron, which increases potassium loss. Deflazacort, a corticosteroid, has mineralocorticoid activity that can also lower potassium, so the effects may add together.
How serious is the interaction between Deflazacort and Penicillin g?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium during high-dose penicillin G therapy with deflazacort and replace potassium as needed.
What other medicines interact with Penicillin g?
MediHelp also lists interactions of Penicillin g with, for example, Amifampridine, Amiloride, Bcg vaccine live. The full list is on the Penicillin g page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
