藥物交互作用
Betrixaban + Tirofiban
嚴重程度: 嚴重
Betrixaban and Tirofiban: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Combining a glycoprotein IIb/IIIa inhibitor with a factor Xa inhibitor raises the risk of serious bleeding. Both agents impair hemostasis through different pathways.
用白話說明這項交互作用的意義
Betrixaban and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive pharmacodynamic effects: factor Xa inhibition by betrixaban plus inhibition of platelet aggregation by tirofiban.
處置方式
Avoid the combination where possible, or limit its duration and monitor closely for bleeding and falls in hemoglobin. Reassess the need for both agents daily.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Tirofiban 的其他交互作用
常見問題
Can I take Betrixaban with Tirofiban?
MediHelp rates the interaction as major. Betrixaban and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining a glycoprotein IIb/IIIa inhibitor with a factor Xa inhibitor raises the risk of serious bleeding. Both agents impair hemostasis through different pathways.
How serious is the interaction between Betrixaban and Tirofiban?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, or limit its duration and monitor closely for bleeding and falls in hemoglobin. Reassess the need for both agents daily.
What other medicines interact with Tirofiban?
MediHelp also lists interactions of Tirofiban with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Tirofiban page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
