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藥品參考

Tirofiban

Tirofiban is a medicine in the class cardiovascular. It is used for acute coronary syndrome.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Cardiovascular
常見劑型
輸注液, 注射劑, 溶液
常見規格
12.5 mg/50 ml, 0.25 mg/ml, 12.5 mg
已知交互作用
43 (嚴重: 20 · 中度: 13 · 輕微: 10)
商品名
12
國家與市場
4

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Blocks binding of fibrinogen and von Willebrand factor to glycoprotein IIb/IIIa receptor on platelet surface; inhibits platelet aggregation

成人常用劑量(仿單摘要)

Acute Coronary Syndrome: Loading dose: 25 mcg/kg IV infused within 5 min, THEN Post loading dose infusion: 0.15 mcg/kg/min IV for up to 18 hr

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown Case reports have not linked it to birth defects or other harm; no fetal harm in rats or rabbits at higher doses. Untreated heart attack can be fatal to mother and fetus. Bleeding is the main risk, especially near delivery. Use if clearly needed.
哺乳
Safe No human milk data; present in rat milk. Given IV and poorly absorbed orally, so the infant is unlikely to absorb meaningful amounts. LactMed: not a reason to stop breastfeeding; watch the infant for bruising or bleeding.

已通報的副作用

  • Dizziness
  • Bradycardia
  • Bleeding
  • Pelvic pain
  • Coronary artery dissection
  • Lower extremity pain

哪些人需要特別留意

  • Concomitant use of fibrinolytics, anticoagulants and antiplatelet drugs increases risk of bleeding
  • Profound thrombocytopenia reported; monitor platelet counts beginning about 6 hr after treatment initiation and daily thereafter

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

重要交互作用 (43)

All 43 interactions, with severity and what to do

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Tirofiban 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Paediatric dosing
  • Patient counselling points
  • Food interactions

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同類別的其他藥品

常見問題

What is Tirofiban used for?

Tirofiban is a medicine in the class cardiovascular. It is used for Acute coronary syndrome.

What side effects have been reported with Tirofiban?

Dizziness, Bradycardia, Bleeding, Pelvic pain, Coronary artery dissection, Lower extremity pain.

Can Tirofiban be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Case reports have not linked it to birth defects or other harm; no fetal harm in rats or rabbits at higher doses. Untreated heart attack can be fatal to mother and fetus. Bleeding is the main risk, especially near delivery. Use if clearly needed. Breastfeeding: Safe. No human milk data; present in rat milk. Given IV and poorly absorbed orally, so the infant is unlikely to absorb meaningful amounts. LactMed: not a reason to stop breastfeeding; watch the infant for bruising or bleeding.

What does Tirofiban interact with?

MediHelp lists 43 known interactions for Tirofiban. Major: 20 · Moderate: 13 · Minor: 10. The most serious include Abrocitinib, Acalabrutinib, Acetylsalicylic acid.

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