藥物交互作用
Capecitabine + Dengue vaccine
嚴重程度: 嚴重
Capecitabine and Dengue vaccine: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Dengue vaccine is a live attenuated vaccine, and capecitabine-induced immunosuppression may both reduce the immune response and increase the risk of vaccine-related infection. Vaccination during chemotherapy is generally inappropriate.
用白話說明這項交互作用的意義
Capecitabine and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Cytotoxic immunosuppression impairs response to the vaccine and permits replication of live attenuated virus.
處置方式
Avoid live vaccines during chemotherapy and give them only after immune recovery as advised by the specialist team.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Capecitabine 的其他交互作用
常見問題
Can I take Capecitabine with Dengue vaccine?
MediHelp rates the interaction as major. Capecitabine and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine is a live attenuated vaccine, and capecitabine-induced immunosuppression may both reduce the immune response and increase the risk of vaccine-related infection. Vaccination during chemotherapy is generally inappropriate.
How serious is the interaction between Capecitabine and Dengue vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and give them only after immune recovery as advised by the specialist team.
What other medicines interact with Capecitabine?
MediHelp also lists interactions of Capecitabine with, for example, Adenovirus types 4 and 7 live, Arsenic trioxide, Axicabtagene ciloleucel. The full list is on the Capecitabine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
