藥物交互作用
Carbenoxolone + Furosemide
嚴重程度: 嚴重
Carbenoxolone and Furosemide: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Carbenoxolone has mineralocorticoid-like activity causing sodium retention and potassium loss, which adds to furosemide-induced hypokalemia. It may also oppose diuretic and antihypertensive effects.
用白話說明這項交互作用的意義
Carbenoxolone and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Inhibition of 11-beta-hydroxysteroid dehydrogenase causes mineralocorticoid excess, additive with loop diuretic kaliuresis.
處置方式
Monitor serum potassium and blood pressure closely and supplement potassium, or avoid the combination in patients with heart disease or on digoxin.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Furosemide 的其他交互作用
常見問題
Can I take Carbenoxolone with Furosemide?
MediHelp rates the interaction as major. Carbenoxolone and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carbenoxolone has mineralocorticoid-like activity causing sodium retention and potassium loss, which adds to furosemide-induced hypokalemia. It may also oppose diuretic and antihypertensive effects.
How serious is the interaction between Carbenoxolone and Furosemide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and blood pressure closely and supplement potassium, or avoid the combination in patients with heart disease or on digoxin.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Cephaloridine. The full list is on the Furosemide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
