藥物交互作用
Cephaloridine + Furosemide
嚴重程度: 嚴重
Cephaloridine and Furosemide: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in general use, and loop diuretics were reported to increase its renal toxicity. The combination could cause acute tubular injury, particularly with volume depletion.
用白話說明這項交互作用的意義
Cephaloridine and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive proximal tubular toxicity, with diuretic-induced volume depletion increasing renal cephaloridine accumulation.
處置方式
Avoid the combination and choose a less nephrotoxic antibiotic. If it cannot be avoided, monitor renal function closely and maintain hydration.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Furosemide 的其他交互作用
常見問題
Can I take Cephaloridine with Furosemide?
MediHelp rates the interaction as major. Cephaloridine and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in general use, and loop diuretics were reported to increase its renal toxicity. The combination could cause acute tubular injury, particularly with volume depletion.
How serious is the interaction between Cephaloridine and Furosemide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a less nephrotoxic antibiotic. If it cannot be avoided, monitor renal function closely and maintain hydration.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
