藥物交互作用
Caspofungin + Phenytoin
嚴重程度: 中度
Caspofungin and Phenytoin: moderate interaction.
最後更新
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摘要
Phenytoin, an enzyme inducer, may lower caspofungin exposure. Reduced antifungal exposure could compromise treatment of invasive fungal infection.
用白話說明這項交互作用的意義
Caspofungin and Phenytoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Caspofungin belongs to Anti Fungals; Phenytoin belongs to Central Nervous System.
為什麼會發生
Phenytoin induces hepatic enzymes and possibly transport pathways, increasing caspofungin clearance.
處置方式
Consider caspofungin 70 mg daily after the loading dose in adults when given with phenytoin, and monitor clinical response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Caspofungin 的其他交互作用
Phenytoin 的其他交互作用
常見問題
Can I take Caspofungin with Phenytoin?
MediHelp rates the interaction as moderate. Caspofungin and Phenytoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phenytoin, an enzyme inducer, may lower caspofungin exposure. Reduced antifungal exposure could compromise treatment of invasive fungal infection.
How serious is the interaction between Caspofungin and Phenytoin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider caspofungin 70 mg daily after the loading dose in adults when given with phenytoin, and monitor clinical response.
What other medicines interact with Caspofungin?
MediHelp also lists interactions of Caspofungin with, for example, Apalutamide, Carbamazepine, Cyclosporin. The full list is on the Caspofungin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
