藥物交互作用
Caspofungin + Cyclosporin
嚴重程度: 中度
Caspofungin and Cyclosporin: moderate interaction.
最後更新
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摘要
Cyclosporine raises caspofungin exposure, and transient elevations of liver transaminases have been seen with the combination. Caspofungin does not materially change cyclosporine levels.
用白話說明這項交互作用的意義
Caspofungin and Cyclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Caspofungin belongs to Anti Fungals; Cyclosporin belongs to Miscellaneous.
為什麼會發生
Cyclosporine inhibits OATP1B1-mediated hepatic uptake of caspofungin, raising its plasma concentrations.
處置方式
Monitor liver enzymes during concurrent therapy and discontinue if clinically significant hepatotoxicity develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cyclosporin 的其他交互作用
Caspofungin 的其他交互作用
常見問題
Can I take Caspofungin with Cyclosporin?
MediHelp rates the interaction as moderate. Caspofungin and Cyclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine raises caspofungin exposure, and transient elevations of liver transaminases have been seen with the combination. Caspofungin does not materially change cyclosporine levels.
How serious is the interaction between Caspofungin and Cyclosporin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor liver enzymes during concurrent therapy and discontinue if clinically significant hepatotoxicity develops.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
