藥物交互作用
Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid
嚴重程度: 中度
Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
最後更新
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摘要
Sodium picosulfate is a prodrug that needs colonic bacteria to form its active laxative metabolite. Antibiotics given before bowel preparation may reduce this conversion and result in inadequate bowel cleansing before colonoscopy.
用白話說明這項交互作用的意義
Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibiotic suppression of colonic bacteria that convert sodium picosulfate to its active metabolite.
處置方式
Where possible, avoid starting the antibiotic before the preparation, or complete the course earlier. Confirm adequate bowel cleansing before the procedure.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefaclor 的其他交互作用
常見問題
Can I take Cefaclor with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that needs colonic bacteria to form its active laxative metabolite. Antibiotics given before bowel preparation may reduce this conversion and result in inadequate bowel cleansing before colonoscopy.
How serious is the interaction between Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, avoid starting the antibiotic before the preparation, or complete the course earlier. Confirm adequate bowel cleansing before the procedure.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
