藥物交互作用
Cefditoren + Kanamycin
嚴重程度: 中度
Cefditoren and Kanamycin: moderate interaction.
最後更新
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摘要
Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been associated with additive kidney injury when combined with them. The effect is mainly reported with parenteral aminoglycosides in patients with other risk factors.
用白話說明這項交互作用的意義
Cefditoren and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Possible additive nephrotoxicity; the aminoglycoside itself causes proximal tubular and cochlear toxicity.
處置方式
Monitor serum creatinine and aminoglycoside levels, keep the patient well hydrated, and adjust doses for renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefditoren 的其他交互作用
常見問題
Can I take Cefditoren with Kanamycin?
MediHelp rates the interaction as moderate. Cefditoren and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been associated with additive kidney injury when combined with them. The effect is mainly reported with parenteral aminoglycosides in patients with other risk factors.
How serious is the interaction between Cefditoren and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and aminoglycoside levels, keep the patient well hydrated, and adjust doses for renal function.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。