藥物交互作用
Cisatracurium + Fentanyl intranasal
嚴重程度: 嚴重
Cisatracurium and Fentanyl intranasal: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Fentanyl causes respiratory depression, sedation and hypotension, and these effects add to those of a neuromuscular blocker when ventilation is inadequate. Cisatracurium is given only with ventilatory support, but residual blockade plus opioid effect can delay safe recovery.
用白話說明這項交互作用的意義
Cisatracurium and Fentanyl intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive respiratory depression from central opioid effect and peripheral neuromuscular blockade.
處置方式
Use only in settings with airway and ventilatory support and monitor neuromuscular blockade, respiration and blood pressure. Reduce doses as needed.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cisatracurium 的其他交互作用
常見問題
Can I take Cisatracurium with Fentanyl intranasal?
MediHelp rates the interaction as major. Cisatracurium and Fentanyl intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fentanyl causes respiratory depression, sedation and hypotension, and these effects add to those of a neuromuscular blocker when ventilation is inadequate. Cisatracurium is given only with ventilatory support, but residual blockade plus opioid effect can delay safe recovery.
How serious is the interaction between Cisatracurium and Fentanyl intranasal?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only in settings with airway and ventilatory support and monitor neuromuscular blockade, respiration and blood pressure. Reduce doses as needed.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
