藥物交互作用
Capreomycin + Cisatracurium
嚴重程度: 嚴重
Capreomycin and Cisatracurium: major interaction.
最後更新
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摘要
Capreomycin has its own neuromuscular blocking activity and can potentiate and prolong the effect of cisatracurium. This may result in prolonged paralysis and respiratory failure.
用白話說明這項交互作用的意義
Capreomycin and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive nondepolarizing-type neuromuscular blockade from capreomycin at the neuromuscular junction.
處置方式
Avoid if possible; otherwise reduce the cisatracurium dose and monitor with train-of-four, with ventilatory support available until full recovery.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cisatracurium 的其他交互作用
常見問題
Can I take Capreomycin with Cisatracurium?
MediHelp rates the interaction as major. Capreomycin and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin has its own neuromuscular blocking activity and can potentiate and prolong the effect of cisatracurium. This may result in prolonged paralysis and respiratory failure.
How serious is the interaction between Capreomycin and Cisatracurium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise reduce the cisatracurium dose and monitor with train-of-four, with ventilatory support available until full recovery.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。