藥物交互作用
Clozapine + Miglitol
嚴重程度: 中度
Clozapine and Miglitol: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Clozapine may cause hyperglycemia and insulin resistance, reducing the effectiveness of antidiabetic therapy such as miglitol. Glycemic control may worsen.
用白話說明這項交互作用的意義
Clozapine and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Clozapine belongs to Central Nervous System; Miglitol belongs to Endocrine.
為什麼會發生
Clozapine-induced insulin resistance opposes the glucose-lowering effect of miglitol.
處置方式
Monitor blood glucose and HbA1c more often and adjust the antidiabetic regimen. Reassess when clozapine is changed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Clozapine 的其他交互作用
Miglitol 的其他交互作用
常見問題
Can I take Clozapine with Miglitol?
MediHelp rates the interaction as moderate. Clozapine and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Clozapine may cause hyperglycemia and insulin resistance, reducing the effectiveness of antidiabetic therapy such as miglitol. Glycemic control may worsen.
How serious is the interaction between Clozapine and Miglitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c more often and adjust the antidiabetic regimen. Reassess when clozapine is changed.
What other medicines interact with Clozapine?
MediHelp also lists interactions of Clozapine with, for example, Deferiprone, Irinotecan, Pimozide. The full list is on the Clozapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
