藥物交互作用
Cyclosporin + Leniolisib
嚴重程度: 嚴重
Cyclosporin and Leniolisib: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Cyclosporine inhibits BCRP and may raise leniolisib exposure, increasing adverse effects.
用白話說明這項交互作用的意義
Cyclosporin and Leniolisib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cyclosporin belongs to Miscellaneous; Leniolisib belongs to Miscellaneous.
為什麼會發生
BCRP inhibition by cyclosporine reduces leniolisib efflux and increases its exposure.
處置方式
Avoid concurrent use if possible; otherwise monitor for leniolisib adverse effects and consider an alternative immunosuppressant.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Leniolisib 的其他交互作用
Cyclosporin 的其他交互作用
常見問題
Can I take Cyclosporin with Leniolisib?
MediHelp rates the interaction as major. Cyclosporin and Leniolisib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cyclosporine inhibits BCRP and may raise leniolisib exposure, increasing adverse effects.
How serious is the interaction between Cyclosporin and Leniolisib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use if possible; otherwise monitor for leniolisib adverse effects and consider an alternative immunosuppressant.
What other medicines interact with Leniolisib?
MediHelp also lists interactions of Leniolisib with, for example, Amobarbital, Apalutamide, Carbamazepine. The full list is on the Leniolisib page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
