藥物交互作用
Dabigatran etexilate + Mifepristone
嚴重程度: 禁忌併用
Dabigatran etexilate and Mifepristone: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Mifepristone is used for medical termination of pregnancy and can cause prolonged or heavy uterine bleeding. In a patient receiving dabigatran etexilate, the impaired haemostasis can turn this into excessive or hazardous haemorrhage.
用白話說明這項交互作用的意義
Dabigatran etexilate and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dabigatran etexilate belongs to Cardiovascular; Mifepristone belongs to Endocrine.
為什麼會發生
Additive haemorrhagic risk (uterine bleeding plus anticoagulation)
處置方式
Mifepristone labelling contraindicates concurrent anticoagulant therapy; use an alternative approach or manage anticoagulation specialist-led before any termination.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Dabigatran etexilate 的其他交互作用
Mifepristone 的其他交互作用
常見問題
Can I take Dabigatran etexilate with Mifepristone?
MediHelp rates the interaction as contraindicated. Dabigatran etexilate and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is used for medical termination of pregnancy and can cause prolonged or heavy uterine bleeding. In a patient receiving dabigatran etexilate, the impaired haemostasis can turn this into excessive or hazardous haemorrhage.
How serious is the interaction between Dabigatran etexilate and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Mifepristone labelling contraindicates concurrent anticoagulant therapy; use an alternative approach or manage anticoagulation specialist-led before any termination.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Dabigatran etexilate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
