藥物交互作用
Deferiprone + Idarubicin
嚴重程度: 嚴重
Deferiprone and Idarubicin: major interaction.
最後更新
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摘要
Deferiprone can cause neutropenia and agranulocytosis, and idarubicin is strongly myelosuppressive. Together the risk of severe, potentially fatal infection is increased.
用白話說明這項交互作用的意義
Deferiprone and Idarubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferiprone belongs to Miscellaneous; Idarubicin belongs to Oncology.
為什麼會發生
Additive bone marrow suppression (pharmacodynamic).
處置方式
Avoid if an alternative iron chelation approach is feasible; otherwise monitor absolute neutrophil count more frequently and interrupt deferiprone for neutropenia.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Idarubicin 的其他交互作用
Deferiprone 的其他交互作用
常見問題
Can I take Deferiprone with Idarubicin?
MediHelp rates the interaction as major. Deferiprone and Idarubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferiprone can cause neutropenia and agranulocytosis, and idarubicin is strongly myelosuppressive. Together the risk of severe, potentially fatal infection is increased.
How serious is the interaction between Deferiprone and Idarubicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if an alternative iron chelation approach is feasible; otherwise monitor absolute neutrophil count more frequently and interrupt deferiprone for neutropenia.
What other medicines interact with Idarubicin?
MediHelp also lists interactions of Idarubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclophosphamide. The full list is on the Idarubicin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
