藥物交互作用
Deferiprone + Interferon beta 1b
嚴重程度: 嚴重
Deferiprone and Interferon beta 1b: major interaction.
最後更新
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摘要
Deferiprone can cause neutropenia and agranulocytosis, and interferon beta can also lower white cell counts. Combined use may increase the risk of severe neutropenia and serious infection.
用白話說明這項交互作用的意義
Deferiprone and Interferon beta 1b can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferiprone belongs to Miscellaneous; Interferon beta 1b belongs to Central Nervous System.
為什麼會發生
Additive myelosuppressive effects on neutrophils.
處置方式
Avoid the combination if an alternative exists. If both are necessary, monitor absolute neutrophil count more often than usual and stop deferiprone if neutropenia develops.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Interferon beta 1b 的其他交互作用
Deferiprone 的其他交互作用
常見問題
Can I take Deferiprone with Interferon beta 1b?
MediHelp rates the interaction as major. Deferiprone and Interferon beta 1b can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferiprone can cause neutropenia and agranulocytosis, and interferon beta can also lower white cell counts. Combined use may increase the risk of severe neutropenia and serious infection.
How serious is the interaction between Deferiprone and Interferon beta 1b?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if an alternative exists. If both are necessary, monitor absolute neutrophil count more often than usual and stop deferiprone if neutropenia develops.
What other medicines interact with Interferon beta 1b?
MediHelp also lists interactions of Interferon beta 1b with, for example, Axicabtagene ciloleucel, Brexucabtagene autoleucel, Ciltacabtagene autoleucel. The full list is on the Interferon beta 1b page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。