藥物交互作用
Deflazacort + Influenza virus vaccine quadrivalent intranasal
嚴重程度: 禁忌併用
Deflazacort and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
用白話說明這項交互作用的意義
Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Glucocorticoid immunosuppression impairs clearance of live attenuated virus and the vaccine immune response.
處置方式
Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Deflazacort 的其他交互作用
常見問題
Can I take Deflazacort with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
How serious is the interaction between Deflazacort and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine. The full list is on the Deflazacort page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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