藥物交互作用
Demeclocycline + Magnesium citrate
嚴重程度: 中度
Demeclocycline and Magnesium citrate: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Magnesium forms insoluble chelates with tetracyclines such as demeclocycline in the gut, markedly reducing absorption. The laxative effect may also speed transit and further lower absorption, risking treatment failure.
用白話說明這項交互作用的意義
Demeclocycline and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Chelation of demeclocycline by magnesium in the gastrointestinal tract reduces absorption.
處置方式
Separate doses so demeclocycline is taken at least 2 hours before or 4 hours after magnesium citrate. Consider a different laxative if possible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium citrate 的其他交互作用
常見問題
Can I take Demeclocycline with Magnesium citrate?
MediHelp rates the interaction as moderate. Demeclocycline and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium forms insoluble chelates with tetracyclines such as demeclocycline in the gut, markedly reducing absorption. The laxative effect may also speed transit and further lower absorption, risking treatment failure.
How serious is the interaction between Demeclocycline and Magnesium citrate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses so demeclocycline is taken at least 2 hours before or 4 hours after magnesium citrate. Consider a different laxative if possible.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Ciprofloxacin, Baloxavir marboxil, Bictegravir. The full list is on the Magnesium citrate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
