藥物交互作用
Cabotegravir + Magnesium citrate
嚴重程度: 中度
Cabotegravir and Magnesium citrate: moderate interaction.
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摘要
Oral cabotegravir can chelate with polyvalent cations such as magnesium, lowering its absorption. This may reduce efficacy of the integrase inhibitor.
用白話說明這項交互作用的意義
Cabotegravir and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabotegravir belongs to Anti Virals; Magnesium citrate belongs to Gastrointestinal Tract.
為什麼會發生
Chelation of cabotegravir by magnesium in the gut reduces absorption.
處置方式
Take oral cabotegravir at least 2 hours before or 4 hours after magnesium citrate.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium citrate 的其他交互作用
Cabotegravir 的其他交互作用
常見問題
Can I take Cabotegravir with Magnesium citrate?
MediHelp rates the interaction as moderate. Cabotegravir and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral cabotegravir can chelate with polyvalent cations such as magnesium, lowering its absorption. This may reduce efficacy of the integrase inhibitor.
How serious is the interaction between Cabotegravir and Magnesium citrate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oral cabotegravir at least 2 hours before or 4 hours after magnesium citrate.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Ciprofloxacin, Baloxavir marboxil, Bictegravir. The full list is on the Magnesium citrate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。