藥物交互作用
Dimercaprol + Ferrous sulfate
嚴重程度: 嚴重
Dimercaprol and Ferrous sulfate: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Dimercaprol forms toxic complexes with iron and is not recommended in iron poisoning. The resulting iron-dimercaprol complex can be harmful to the kidneys and is of no benefit for iron removal. Oral iron should not be given with dimercaprol during chelation therapy.
用白話說明這項交互作用的意義
Dimercaprol and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Dimercaprol forms a chelate with iron that is toxic and may worsen toxicity rather than promoting safe elimination.
處置方式
Do not use dimercaprol to treat iron overload or iron poisoning; use deferoxamine instead. Hold iron supplements while dimercaprol is being given.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ferrous sulfate 的其他交互作用
常見問題
Can I take Dimercaprol with Ferrous sulfate?
MediHelp rates the interaction as major. Dimercaprol and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dimercaprol forms toxic complexes with iron and is not recommended in iron poisoning. The resulting iron-dimercaprol complex can be harmful to the kidneys and is of no benefit for iron removal. Oral iron should not be given with dimercaprol during chelation therapy.
How serious is the interaction between Dimercaprol and Ferrous sulfate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use dimercaprol to treat iron overload or iron poisoning; use deferoxamine instead. Hold iron supplements while dimercaprol is being given.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous sulfate page.
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在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
