藥物交互作用
Calcium carbonate + Ferrous sulfate
嚴重程度: 中度
Calcium carbonate and Ferrous sulfate: moderate interaction.
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摘要
Calcium carbonate reduces absorption of oral iron, partly by raising gastric pH and by competing for uptake. This can blunt the response to iron therapy.
用白話說明這項交互作用的意義
Calcium carbonate and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Ferrous sulfate belongs to Miscellaneous.
為什麼會發生
Higher gastric pH and calcium competition decrease non-heme iron solubility and absorption.
處置方式
Separate ferrous sulfate and calcium carbonate by at least 2 hours. Monitor hemoglobin and ferritin.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Calcium carbonate 的其他交互作用
Ferrous sulfate 的其他交互作用
常見問題
Can I take Calcium carbonate with Ferrous sulfate?
MediHelp rates the interaction as moderate. Calcium carbonate and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium carbonate reduces absorption of oral iron, partly by raising gastric pH and by competing for uptake. This can blunt the response to iron therapy.
How serious is the interaction between Calcium carbonate and Ferrous sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate ferrous sulfate and calcium carbonate by at least 2 hours. Monitor hemoglobin and ferritin.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。