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藥物交互作用

Calcium carbonate + Ferrous sulfate

嚴重程度: 中度

Calcium carbonate and Ferrous sulfate: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Calcium carbonate reduces absorption of oral iron, partly by raising gastric pH and by competing for uptake. This can blunt the response to iron therapy.

用白話說明這項交互作用的意義

Calcium carbonate and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Calcium carbonate belongs to Gastrointestinal Tract; Ferrous sulfate belongs to Miscellaneous.

證據等級: Moderate

為什麼會發生

Higher gastric pH and calcium competition decrease non-heme iron solubility and absorption.

處置方式

Separate ferrous sulfate and calcium carbonate by at least 2 hours. Monitor hemoglobin and ferritin.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Calcium carbonate with Ferrous sulfate?

MediHelp rates the interaction as moderate. Calcium carbonate and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium carbonate reduces absorption of oral iron, partly by raising gastric pH and by competing for uptake. This can blunt the response to iron therapy.

How serious is the interaction between Calcium carbonate and Ferrous sulfate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate ferrous sulfate and calcium carbonate by at least 2 hours. Monitor hemoglobin and ferritin.

What other medicines interact with Calcium carbonate?

MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.

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