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藥物交互作用

Ergoloid mesylates + Naratriptan

嚴重程度: 禁忌併用

Ergoloid mesylates and Naratriptan: contraindicated interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Both drugs act on serotonergic and vascular receptors, so additive vasoconstriction is possible. Ergoloid's vasoconstrictor activity is modest, but triptan labeling cautions against ergot-type drugs.

用白話說明這項交互作用的意義

Ergoloid mesylates and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

證據等級: Low

為什麼會發生

Additive vasoconstriction through serotonin receptor agonism and ergot-derived receptor effects.

處置方式

Avoid use together and separate by at least 24 hours. Reconsider the need for ergoloid in patients with migraine.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Ergoloid mesylates with Naratriptan?

MediHelp rates the interaction as contraindicated. Ergoloid mesylates and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs act on serotonergic and vascular receptors, so additive vasoconstriction is possible. Ergoloid's vasoconstrictor activity is modest, but triptan labeling cautions against ergot-type drugs.

How serious is the interaction between Ergoloid mesylates and Naratriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid use together and separate by at least 24 hours. Reconsider the need for ergoloid in patients with migraine.

What other medicines interact with Naratriptan?

MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Naratriptan page.

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