藥物交互作用
Insulin aspart-insulin aspart protamine + Pentamidine
嚴重程度: 嚴重
Insulin aspart-insulin aspart protamine and Pentamidine: major interaction.
最後更新
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摘要
Pentamidine can damage pancreatic beta cells, causing early hypoglycemia from insulin release and later hyperglycemia or diabetes. Glucose control in insulin-treated patients may therefore become unpredictable.
用白話說明這項交互作用的意義
Insulin aspart-insulin aspart protamine and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin aspart-insulin aspart protamine belongs to Endocrine; Pentamidine belongs to Anti Parasitic.
為什麼會發生
Pentamidine is toxic to pancreatic beta cells, causing biphasic dysglycemia that interacts with exogenous insulin.
處置方式
Monitor blood glucose frequently during and after pentamidine therapy and adjust insulin doses promptly.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin aspart-insulin aspart protamine 的其他交互作用
- Ethanol + Insulin aspart-insulin aspart protamine 嚴重
- Insulin aspart-insulin aspart protamine + Pioglitazone 嚴重
- Insulin aspart-insulin aspart protamine + Rosiglitazone 嚴重
- Acarbose + Insulin aspart-insulin aspart protamine 中度
- Albiglutide + Insulin aspart-insulin aspart protamine 中度
- Alogliptin + Insulin aspart-insulin aspart protamine 中度
Pentamidine 的其他交互作用
常見問題
Can I take Insulin aspart-insulin aspart protamine with Pentamidine?
MediHelp rates the interaction as major. Insulin aspart-insulin aspart protamine and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pentamidine can damage pancreatic beta cells, causing early hypoglycemia from insulin release and later hyperglycemia or diabetes. Glucose control in insulin-treated patients may therefore become unpredictable.
How serious is the interaction between Insulin aspart-insulin aspart protamine and Pentamidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose frequently during and after pentamidine therapy and adjust insulin doses promptly.
What other medicines interact with Insulin aspart-insulin aspart protamine?
MediHelp also lists interactions of Insulin aspart-insulin aspart protamine with, for example, Ethanol, Pioglitazone, Rosiglitazone. The full list is on the Insulin aspart-insulin aspart protamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
